Drug Dosage and Treatment Optimization
Genomic Data Analytics Platform
The Challenge
The solution should analyze patient's genome for structural information of T-cell receptors (TCR), major histocompatibility complexes (MHC), and antigens, thus, being able to select antigens with best fit to TCR and MHC of tumor cells and ignite an immunoresponse.
Value Delivered
The developed pipeline processes patient genome data and applies multiple AI/ML models to predict
antigen class (antigen/neoantigen)
compatibility between antigens and MHCs
compatibility between antigens and TCRs.
and provide most confident neoantigen candidates
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